Official websites use. Share sensitive information only on official, secure websites. It is released into the environment through natural processes and human activities and accumulates in aquatic environments.
This review compiles scientific data on the neurotoxicity of aluminium contamination on the nervous system of aquatic organisms. More precisely, it helps identify biomarkers of aluminium exposure for aquatic environment biomonitoring in freshwater aquatic vertebrates.
Al is neurotoxic and accumulates in the nervous system of aquatic vertebrates, which is why it could be responsible for oxidative stress. In addition, it activates and inhibits antioxidant enzymes and leads to changes in acetylcholinesterase activity, neurotransmitter levels, and in the expression of several neural genes and nerve cell components.
It also causes histological changes in nerve tissue, modifications of organism behaviour, and cognitive deficit. However, impacts of aluminium exposure on the early stages of aquatic vertebrate development are poorly described. Lastly, this review also poses the question of how accurate aquatic vertebrates fishes and amphibians could be used as model organisms to complement biological data relating to the developmental aspect.
Keywords: aquatic contamination, aluminium, nervous system, development, Xenopus , zebrafish. Since the nineteenth century, anthropogenic activities have significantly altered ecosystems and triggered the sixth biodiversity crisis [ 1 ]. One of the main causes of this biodiversity erosion is the release of micropollutants of diverse nature and origins [ 2 , 3 , 4 ].
