Josefina Lira-Plascencia 1. Objective: To present the perinatal results of two patients diagnosed with Ewing's sarcoma and alveolar rhabdomyosarcoma. Methodology: Two cases of patients with a diagnosis of sarcoma treated at the National Institute of Perinatology in Mexico City were reviewed. Results: Case 1, a year-old female, with a The chest radiograph revealed multiple pulmonary nodules and the magnetic resonance imaging revealed a tumor in the gluteal region with extensive involvement.
The diagnosis was stage IV metastatic Ewing sarcoma. Management consisted of symptomatic treatment with resolution of the pregnancy at 28 weeks. Case 2, a year-old female with a T decompression was performed. Absence of fetal heart rate was evidenced, so medical management of deferred abortion was performed.
The association of cancer and pregnancy is rare, with an incidence of 1 in every 1 pregnancies, with breast cancer, melanoma, cervical cancer, lymphomas and acute leukemia being reported in order of frequency 1 , 2. The diagnosis represents a challenge for the obstetrician due to the low incidence and to the poor maternal-fetal prognosis in the advanced stages of the disease.
Sarcomas are rare primary soft tissue or bone malignant neoplasms. In the period from to , cases were published in the journal Rare tumors, in which 0. The presence of Ewing sarcoma in pregnancy is rare. Between and , only 19 cases associated with pregnancy were reported, including 3 cases of extraskeletal sarcoma.
Regarding rhabdomyosarcoma, between and only 14 cases associated with pregnancy have been reported 5. We present two cases of pregnant women with a diagnosis of Ewing sarcoma and alveolar rhabdomyosarcoma, respectively, treated at the National Institute of Perinatology of Mexico.
