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If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. Incidence rates were calculated per person years py. Using longitudinal mixed models, we analyzed risk factors associated with sexually transmitted infections STIs.
For two, suboptimal adherence was reported and in the third case, suboptimal adherence and resistance to emtricitabine were observed. One infection was likely acquired before PrEP start. Incidence rates were Increased PrEP availability to people at risk of HIV infection through the elimination of barriers requires further attention.
Investigation and monitoring with a longer follow-up would be of value. Infection with the human immunodeficiency virus HIV remains globally endemic with 1. In Germany, HIV transmission remains an issue despite prophylactic measures, and a knowledgeable men who have sex with men MSM population which is the largest affected group. Unfortunately, similar results were not observed in women [ 5 ]. Since the efficacy of PrEP is highly correlated with adherence, an evaluation in the routine clinical care setting would provide further information on PrEP use and outcomes [ 6 ].
Although the use of PrEP significantly reduces the risk of HIV transmission, it may change sexual behavior resulting in an elevated risk for the transmission of other sexually transmitted infections STIs and even HIV [ 7 — 9 ]. On the other hand, PrEP access under medical supervision offers an opportunity for counselling, regular STI screening and appropriate treatment [ 7 ]. PrEP was approved in Germany in and available initially on a self-paying basis [ 10 ]. As a result, it was frequently obtained from informal sources outside of the health care system and hence without adequate testing for HIV and other STIs, counselling and monitoring of side effects.
