We studied two groups of constipated patients. Group 2 consisted of 10 patients nine females and one male without hypertonicity; age was Group 3 consisted of eight asymptomatic controls four females and four males ; age was After a minute resting pressure recording of the UAS with a water-filled balloon, the probe was pulled through the outside and the UAS was assessed after spreading 5 mg of placebo and then 5 mg of NTG on the balloon. None of the subjects experienced a decrease of PP5 vs.
All patients in Group 1 Delay of the pressure decrease was less than two minutes, with wide interindividual variability of duration of the pressure decrease. Mild side effectsβanal pain and transient headacheβwere reported in five patients.
NTG has to be evaluated in anal pathology, especially in patients with hypertonic sphincter terminal constipation or acute hypertonicity of the sphincter due to a fissure. This is a preview of subscription content, log in via an institution to check access. Institutional subscriptions.
Mechanisms of idiopathic constipation: outlet obstruction. Gastroenterology ;β PubMed Google Scholar. Function of the internal anal sphincter and rectal sensitivity in idiopathic constipation.
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