Official websites use. Share sensitive information only on official, secure websites. Correspondence: ivan. Background: The facilitation of early recovery of acute kidney injury AKI is an important step to improve outcome, particularly because of the limited therapeutic interventions currently available for AKI.
The combination of an electronic alert and biomarker-guided kidney-protection strategy implemented in the routine care may have an impact on the incidence of early complete reversal of AKI after major non-cardiac surgery. Data collection required 6 months for each cohort.
Intervention was stratified according to three levels of immediate AKI risk: low, moderate, and high. Primary outcome was early AKI recovery, i.
Patients with AKI reversal within the first 7 postoperative days had lower in-hospital mortality than patients without AKI reversal. Conclusions: Implementing a combined electronic alert and biomarker-guided kidney-protection strategy in routine care improved early recovery of AKI after major surgery. The second most frequently reported etiology of acute kidney injury AKI of intensive care patients is major surgery.
Incidence rates of AKI after surgery vary between 6. However, despite the growing knowledge in the field of postoperative care, AKI carries the risk of both short-term and long-term mortality [ 5 , 6 ] and causes high costs for public health-care systems [ 7 , 8 , 9 ]. Recent advances in AKI research have enabled a shift from solely assessing the functional renal markers creatinine and urine output to monitoring changes on the cellular level—subclinical injury—before altering renal function with new biomarkers [ 10 , 11 , 12 , 13 ].
