Official websites use. Share sensitive information only on official, secure websites. Author for Correspondence: Catherine E. Post-exposure prophylaxis PEP is a useful HIV prevention strategy if individuals are able to identify high-risk exposures and seek timely care, however to date there has been limited data on the use of PEP by CM users.
Multivariable models were used to assess the association between CM use during exposure 7. Keywords: post-exposure prophylaxis, HIV prevention, crystal methamphetamine, men who have sex with men. Crystal methamphetamine is a highly addictive psychostimulant that has been linked to high-risk sexual behavior and incident HIV infection among men who have sex with men MSM.
Gonzales et al. Colfax and Shoptaw, ; Mimiaga et al. Benotsch et al. Post-exposure prophylaxis PEP consists of a day course of antiretroviral therapy ART given prophylactically within 72 hours of a high-risk exposure. Smith et al. Cardo et al. Landovitz et al. Liu et al. The purpose of the present study is two-fold. Firstly, we sought to characterize the effect of event-level and chronic crystal methamphetamine use and sexual risk behavior during the exposure that led to PEP, compared to individuals who accessed PEP but had not used crystal methamphetamine.
Event-level crystal methamphetamine use may affect risk-taking behavior differentially compared to chronic use, and thus we attempt to understand the effect of crystal methamphetamine use at the time of event independently of whether or not the individual is a chronic methamphetamine user. Secondly, we sought to assess the relationship between repeat PEP use and long-term outcomes following presentation for PEP in MSM with crystal methamphetamine use compared to those who had not used crystal methamphetamine.
A better understanding of the context of risk prior to, and after, first PEP use and the trajectory of subsequent PEP use among MSM who use crystal methamphetamine will help to inform the optimal deployment of biomedical HIV prevention strategies for this group of MSM.
