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Official websites use. Share sensitive information only on official, secure websites. This study investigates their relationship with sexual quality of life, focusing on dyspareunia and related dysfunctions, as assessed using the Female Sexual Function Index FSFI.
Dyspareunia, a prominent symptom of endometriosis, is linked to lower FSFI scores in domains such as desire mean 3. Patient factors such as higher endometriosis severity scores mean These findings highlight the complex interplay between biomarkers, individual factors, and sexual dysfunction in endometriosis, underscoring the need for personalized therapeutic approaches. Endometriosis is a chronic disease characterized by the presence of endometrial tissue, consisting of endometrial stroma and glands, outside the uterine cavity.
It is a hormone-dependent pathology, with most cases occurring in patients of reproductive age, with premenarchal or postmenopausal cases being an exception. There are several theories regarding the origin of endometriotic lesions, with some of the most compelling being retrograde menstruation, immune deficiency, and hematogenous or lymphatic dissemination.
The location of endometriotic lesions can be explained through these theories, with the pelvic organs, such as ovaries, fallopian tubes, uterus, and uterosacral ligaments, being most commonly affected.
However, atypical lesions have also been described, such as those on diaphragm, lungs, or other distant organs [ 5 , 6 , 7 , 8 , 9 , 10 , 11 ]. The main symptom of endometriosis is pelvic pain in various forms: dysmenorrhea, dyspareunia, chronic pelvic pain, dysuria when the urinary tract is involved, or dyschezia when the intestines are affected.