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Background: Knee osteoarthritis KOA is a highly prevalent joint disease among the middle-aged and elderly population that can lead to pain, functional impairment, decreased quality of life, and a large number of medical expenses. Physical therapy is one of the main treatment methods for KOA. In China, Tuina has been widely used in the treatment of KOA, but up to now, there is no high-quality medical evidence to support its effectiveness and safety.
The purpose of this study was to objectively evaluate the efficacy and safety of Tuina in the treatment of KOA. Methods: A crossover design clinical trial was performed on 96 patients.
The test group and the control group in the trial were allocated randomly in a ratio of The test group received Tuina treatment for 4 weeks first and then received health education intervention for another 4 weeks. The control group received health education intervention for 4 weeks first and then received Tuina treatment for another 4 weeks. Adverse events during the intervention were collected in both groups. All patients who received Tuina treatment were significantly superior to those who received health education intervention in the WOMAC total score Both groups had no serious adverse events during the treatment.
Conclusion: This trial demonstrated that Tuina can reduce joint pain in patients with KOA and improve the physical functions of the knee joint effectively and safely.
Knee osteoarthritis KOA is a highly prevalent joint disease among middle-aged and elderly people, and it is a leading cause of pain, impaired function, reduction of life quality, and astonishing medical costs for treatment 1 , 2. With an aging population and obesity epidemic, the incidence of KOA has been increasing year by year 4. American College of Rheumatology ACR launched a pyramid scheme of KOA treatment, which was based on measures of education, exercise, and weight reduction, supplementing externally used non-steroidal anti-inflammatory drugs NSAIDs if necessary, adding the use of acetaminophen and NSAIDs orally under the ineffective situation, and performing intra-articular corticosteroid injections during acute attack 6.