Official websites use. Share sensitive information only on official, secure websites. Advanced puberty in girls is defined as the onset of puberty between the ages of 8 yr and 10 yr. Data analysis using multiple linear regression models was performed in 50 girls with advanced puberty who reached their AH after spontaneous puberty. The actual AH The AH was below cm in 7 girls, of whom 3 were characterized by paternal transmission of the advanced puberty.
The AH cm could be calculated at the initial evaluation: 1. The calculated AH We established a formula that can be used at an initial evaluation to predict the AH, and then to assess the risk of reduced AH as a result of advanced puberty. According to this formula, the actual AH was lower than the calculated AH by more than 2. The AHs of the untreated girls with advanced puberty did not differ from those predicted at the initial evaluation by the Bayley and Pinneau table or from the THs.
However, this study provides a useful and ready-to-use formula that can be an additional assessment of girls with advanced puberty. Advanced puberty in girls is defined as the onset of puberty between the ages of 8 and 10 yr. In nearly all cases, advanced puberty, which is a variant of normal puberty, is due to a familial condition rather than a pathological condition.
The premature secretion of estradiol increases the growth rate and accelerates bone maturation, which can shorten the growing period, and it may cause reduced adult height AH. Treatment with gonadotropin-releasing hormone GnRH analog blocks the pituitary-ovarian axis, thereby preventing the secretion of estradiol, slowing the bone age BA progression and preserving growth potential.
This action has been demonstrated in the evolving forms of idiopathic central precocious puberty in girls [ 1 ].
