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Background: There is a lack of data on trends in prescribing of opioid analgesics in Germany based on individual-level data. Further, studies in this field mostly focused on prescription prevalence, while only few studies also considered morphine equivalency as a quantification measure. This study aims to assess trends in prescribing of opioid analgesics in Germany using different quantification measures. We included all persons with continuous insurance or those who died in the respective year and identified all outpatient prescriptions of opioid analgesics prescribed to these persons in the respective year.
In addition, the measures were directly standardized to the German population 31 December Results: The number of eligible persons ranged from 11,, in to 17,, in The standardized prescription prevalence steadily decreased from 5.
The OME per 1, person-years increased in most age and sex groups between and Conclusion: In Germany, the overall prescription prevalence of opioid analgesics decreased between and , while the opposite increase was observed when oral morphine equivalents were considered. Our study illustrates that trends in prescribing of opioid analgesics can strongly depend on the quantification measure being considered.
Article XML version Send article. Doc23gaa23 doi: Outline Top Text. Text Background: There is a lack of data on trends in prescribing of opioid analgesics in Germany based on individual-level data.