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Menopause can have a significant impact on the body, with effects ranging beyond the endocrine and reproductive systems. Learn about the systemic effects of menopause, so you can help patients in your clinics through the transition. Combining tafasitamab with lenalidomide and rituximab significantly improves progression-free survival for patients with relapsed or refractory follicular lymphoma. Keynote series Spotlight on menopause Menopause can have a significant impact on the body, with effects ranging beyond the endocrine and reproductive systems.
Published: Thursday 12 th December Springer Medicine. Search Enter your search terms Search. Current Oncology Reports. Abstract Purpose of review Breast malignancy is the most common cancer in females. Symptoms of pelvic floor disorders and sexual dysfunction secondary to systemic cancer treatment may occur. Non-surgical, non-pharmaceutical conservative therapies, namely pelvic floor muscle PFM and education-based therapies, could be beneficial to reduce these symptoms in this population.
This systematic review aimed to examine the evidence regarding their effectiveness on bladder, bowel, vaginal, sexual, psychological function, quality of life, and PFM function in breast cancer populations. Recent findings Six databases were searched to identify interventional studies on the effect of PFM therapies, education-based therapies, or combined multimodal therapies on any outcome of interest.
The search yielded results, from which 12 studies were included. Findings suggest that PFM therapies active may be beneficial, and education in the format of CBT may improve bladder function. No data were found for bowel function and results from two RCTs were inconclusive to draw conclusions for vaginal function.
Sexual function was the most frequently reported outcome. Given the limited number of studies and their methodological limitations, caution should be exercised when interpreting these study results.