Take full control of your condensates. Labbot can help you fine-tune solution conditions and map out phase behavior in unrivaled detail, giving you a better understanding of how droplets come and go. Take classical methods to new heights with automated measurements. Detect ligand binding or oligomerization with FRET or by tracking changes in intrinsic fluorescence.
Maximize the information obtained from each sample and untangle the complexities of fibril growth. By combining full spectrum readouts with light scattering and exercising complete control over sample conditions, you can easily set up your next amyloid experiment.
Follow protein unfolding with intrinsic fluorescence or external probes while Labbot scans temperature across your defined range. Easily track any resulting aggregation with static light scattering for a full thermal profile of your protein. Labbot's automated titration provides detailed binding curves for a deeper understanding of protein-metal ion interactions. You can obtain your measurement output via absorbance or fluorescence spectroscopy, depending on your assay's needs.
Labbot collects real-time data from an attached pH meter for highly detailed pH titrations, including measuring the isoelectric point of a protein, mapping pH-dependent phase behaviors, or monitoring other pH-affected processes. Complement OD measurements with highly sensitive light scattering and map out the phase behaviour with automatic sample control. Follow how proteins unfold or colloids aggregate as you change the pH step by tiny step with the automatic titration function.
By labelling the protein with a FRET donor and the ligand with a compatible FRET acceptor, we can track the interaction using the decrease in the donor signal. The results are reliable, accurate, and repeatable, with no variation between individual operators. Little training needed to get started. While Labbot is busy executing your instructions you could already be thinking about your next experiment. Labbot uses no proprietary consumables.
